Week
1
Sunday 8:25 PM
September 7, 2025
@
13 - 27
Green Bay
Packers
Detroit Lions Lost. Record: 0-1
Week
2
Sunday 5:00 PM
September 14, 2025
VS.
52 - 21
Chicago
Bears
Detroit Lions Won! Record: 1-1
Week
3
Tuesday 12:15 AM
September 23, 2025
@
38 - 30
Baltimore
Ravens
Detroit Lions Won! Record: 2-1
Week
4
Sunday 5:00 PM
September 28, 2025
VS.
34 - 10
Cleveland
Browns
Detroit Lions Won! Record: 3-1
Week
5
Sunday 8:25 PM
October 5, 2025
@
37 - 24
Cincinnati
Bengals
Detroit Lions Won! Record: 4-1
Week
6
Monday 12:20 AM
October 13, 2025
@
17 - 30
Kansas City
Chiefs
Detroit Lions Lost. Record: 4-2
Week
7
Monday 11:00 PM
October 20, 2025
VS.
24 - 9
Tampa Bay
Buccaneers
Detroit Lions Won! Record: 5-2
Week
9
Sunday 6:00 PM
November 2, 2025
VS.
24 - 27
Minnesota
Vikings
Detroit Lions Lost. Record: 5-3
Week
10
Sunday 9:25 PM
November 9, 2025
@
44 - 22
Washington
Commanders
Detroit Lions Won! Record: 6-3
Week
11
Monday 1:20 AM
November 17, 2025
@
9 - 16
Philadelphia
Eagles
Detroit Lions Lost. Record: 6-4
Week
12
Sunday 6:00 PM
November 23, 2025
VS.
34 - 27
New York
Giants
Detroit Lions Won! Record: 7-4
Week
13
Thursday 6:00 PM
November 27, 2025
VS.
24 - 31
Green Bay
Packers
Detroit Lions Lost. Record: 7-5
Week
14
Friday 1:15 AM
December 5, 2025
VS.
44 - 30
Dallas
Cowboys
Detroit Lions Won! Record: 8-5
Week
15
Sunday 9:25 PM
December 14, 2025
@
34 - 41
Los Angeles
Rams
Detroit Lions Lost. Record: 8-6
Week
16
Sunday 9:25 PM
December 21, 2025
VS.
24 - 29
Pittsburgh
Steelers
Detroit Lions Lost. Record: 8-7
Week
17
Thursday 9:30 PM
December 25, 2025
@
10 - 23
Minnesota
Vikings
Detroit Lions Lost. Record: 8-8
Week
18
Sunday 9:25 PM
January 4, 2026
@
19 - 16
Chicago
Bears
Detroit Lions Won! Record: 9-8