Week
1
Sunday 5:00 PM
September 7, 2025
@
20 - 13
New Orleans
Saints
Arizona Cardinals Won! Record: 1-0
Week
2
Sunday 8:05 PM
September 14, 2025
VS.
27 - 22
Carolina
Panthers
Arizona Cardinals Won! Record: 2-0
Week
3
Sunday 8:25 PM
September 21, 2025
@
15 - 16
San Francisco
49ers
Arizona Cardinals Lost. Record: 2-1
Week
4
Friday 12:15 AM
September 26, 2025
VS.
20 - 23
Seattle
Seahawks
Arizona Cardinals Lost. Record: 2-2
Week
5
Sunday 8:05 PM
October 5, 2025
VS.
21 - 22
Tennessee
Titans
Arizona Cardinals Lost. Record: 2-3
Week
6
Sunday 5:00 PM
October 12, 2025
@
27 - 31
Indianapolis
Colts
Arizona Cardinals Lost. Record: 2-4
Week
7
Sunday 8:25 PM
October 19, 2025
VS.
23 - 27
Green Bay
Packers
Arizona Cardinals Lost. Record: 2-5
Week
9
Tuesday 1:15 AM
November 4, 2025
@
27 - 17
Dallas
Cowboys
Arizona Cardinals Won! Record: 3-5
Week
10
Sunday 9:05 PM
November 9, 2025
@
22 - 44
Seattle
Seahawks
Arizona Cardinals Lost. Record: 3-6
Week
11
Sunday 9:05 PM
November 16, 2025
VS.
22 - 41
San Francisco
49ers
Arizona Cardinals Lost. Record: 3-7
Week
12
Sunday 9:05 PM
November 23, 2025
VS.
24 - 27
Jacksonville
Jaguars
Arizona Cardinals Lost. Record: 3-8
Week
13
Sunday 6:00 PM
November 30, 2025
@
17 - 20
Tampa Bay
Buccaneers
Arizona Cardinals Lost. Record: 3-9
Week
14
Sunday 9:25 PM
December 7, 2025
VS.
17 - 45
Los Angeles
Rams
Arizona Cardinals Lost. Record: 3-10
Week
15
Sunday 6:00 PM
December 14, 2025
@
20 - 40
Houston
Texans
Arizona Cardinals Lost. Record: 3-11
Week
16
Sunday 9:05 PM
December 21, 2025
VS.
19 - 26
Atlanta
Falcons
Arizona Cardinals Lost. Record: 3-12
Week
17
Sunday 6:00 PM
December 28, 2025
@
14 - 37
Cincinnati
Bengals
Arizona Cardinals Lost. Record: 3-13
Week
18
Sunday 9:25 PM
January 4, 2026
@
20 - 37
Los Angeles
Rams
Arizona Cardinals Lost. Record: 3-14