Week 1
September 7, 2025
Sunday 5:00 PM
New Orleans Saints
At.
20 - 13
Arizona Cardinals Won! Record: 1-0
Week 2
September 14, 2025
Sunday 8:05 PM
Carolina Panthers
Vs.
27 - 22
Arizona Cardinals Won! Record: 2-0
Week 3
September 21, 2025
Sunday 8:25 PM
San Francisco 49ers
At.
15 - 16
Arizona Cardinals Lost. Record: 2-1
Week 4
September 26, 2025
Friday 12:15 AM
Seattle Seahawks
Vs.
20 - 23
Arizona Cardinals Lost. Record: 2-2
Week 5
October 5, 2025
Sunday 8:05 PM
Tennessee Titans
Vs.
21 - 22
Arizona Cardinals Lost. Record: 2-3
Week 6
October 12, 2025
Sunday 5:00 PM
Indianapolis Colts
At.
27 - 31
Arizona Cardinals Lost. Record: 2-4
Week 7
October 19, 2025
Sunday 8:25 PM
Green Bay Packers
Vs.
23 - 27
Arizona Cardinals Lost. Record: 2-5
Week 9
November 4, 2025
Tuesday 1:15 AM
Dallas Cowboys
At.
27 - 17
Arizona Cardinals Won! Record: 3-5
Week 10
November 9, 2025
Sunday 9:05 PM
Seattle Seahawks
At.
22 - 44
Arizona Cardinals Lost. Record: 3-6
Week 11
November 16, 2025
Sunday 9:05 PM
San Francisco 49ers
Vs.
22 - 41
Arizona Cardinals Lost. Record: 3-7
Week 12
November 23, 2025
Sunday 9:05 PM
Jacksonville Jaguars
Vs.
24 - 27
Arizona Cardinals Lost. Record: 3-8
Week 13
November 30, 2025
Sunday 6:00 PM
Tampa Bay Buccaneers
At.
17 - 20
Arizona Cardinals Lost. Record: 3-9
Week 14
December 7, 2025
Sunday 9:25 PM
Los Angeles Rams
Vs.
17 - 45
Arizona Cardinals Lost. Record: 3-10
Week 15
December 14, 2025
Sunday 6:00 PM
Houston Texans
At.
20 - 40
Arizona Cardinals Lost. Record: 3-11
Week 16
December 21, 2025
Sunday 9:05 PM
Atlanta Falcons
Vs.
19 - 26
Arizona Cardinals Lost. Record: 3-12
Week 17
December 28, 2025
Sunday 6:00 PM
Cincinnati Bengals
At.
14 - 37
Arizona Cardinals Lost. Record: 3-13
Week 18
January 4, 2026
Sunday 9:25 PM
Los Angeles Rams
At.
20 - 37
Arizona Cardinals Lost. Record: 3-14